Posts Tagged ‘nerve regeneration’

Cancer Drug May Aid Nerve Regeneration after Spinal Cord Injury

Posted on February 3rd, 2011

The cancer drug Taxol has the potential to assist nerve regeneration following a spinal cord injury, according to researchers.

The study, which has been published on the Sciencemag website, details how the drug can help in the regeneration of damaged cells in the central nervous system following a spinal cord injury.

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Potential Spinal Cord Injury Treatments

Posted on August 24th, 2010

There have been several recent developments in the potential treatment of spinal cord injury. A group of researchers showed they were able to enhance the regeneration of nerve connections after spinal cord injury by deleting an enzyme called PTEN. The enzyme controls a molecular pathway called mTOR that is a key regulator of cell growth. During development, when nerve growth and connections occur, PTEN activity is low, allowing cell growth. When growth is completed, PTEN is turned on to inhibit cell growth. Controlled stimulation of cell growth is important for tissue regeneration. The scientists disabled PTEN in mice and were able to achieve nerve growth past a spinal cord lesion. The study published in Nature Neuroscience points to possible strategies to encourage a damaged spinal cord to sprout new neuron growth for repair.

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New Hope for Brain, Spinal Cord Injuries

Posted on December 14th, 2009

Deletion of key gene could help nerve fibers regenerate, researchers say

Deleting a gene that suppresses natural growth factors enables regeneration of injured nerve fibers (axons) in mice, a new study shows.

The finding may lead to new treatments for people with brain and spinal cord injuries.

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Crucial Finding Advances Spinal Cord Injury Research

Posted on August 4th, 2009

Scientists guide axons to re-form nerve connections in rats

In a finding that is a major advance in spinal cord injury research, U.S. scientists report that regenerating axons can be guided to their correct targets where they can re-form connections after spinal cord injury.

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Stem-Cell Breakthrough

Posted on July 28th, 2009

It’s a chilling thought. In the coming year, 130,000 people worldwide will suffer spinal-cord injuries—in a car crash, perhaps, or a fall. More than 90 percent of them will endure at least partial paralysis. There is no cure. But after a decade of hype and controversy over research on embryonic stem cells—cells that could, among other things, potentially repair injured spinal cords—the world’s first clinical trial is about to begin. As early as this month, the first of 10 newly injured Americans, paralyzed from the waist down, will become participants in a study to assess the safety of a conservative, low-dose treatment. If all goes well, researchers will have taken a promising step toward a goal that once would have been considered a miracle—to help the lame walk.

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