Posts Tagged ‘nerve regeneration’
Stem Cell Grafts and Rehabilitation Combined Boost Spinal Cord Injury Results
Posted on October 29th, 2022
In animal models, researchers found that intensive physical therapy in tandem with implanted neural stem cells increased tissue growth, repair, and functionality more than those treatments alone.
In recent years, researchers have made measurable progress, using animal models, to promote tissue regeneration in spinal cord injuries (SCI) through implanted neural stem cells or grafts. Other efforts have shown that intensive physical rehabilitation can improve function after SCI by promoting greater or new roles for undamaged or spared cells and neural circuits.
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Glial Cell Metabolism Linked with Functional Regeneration of CNS Neurons
Posted on September 19th, 2020
Scientists at the Lewis Katz School of Medicine at Temple University (LKSOM) and the University of Pennsylvania have demonstrated how astrocytic glial cells in the brain can play a major role in facilitating neuron repair. The research, reported in Cell Metabolism, is the first to establish a link between glucose metabolism in glial cells and functional regeneration of damaged neurons in the central nervous system. “We found that glia have a metabolic switch associated with glucose metabolism that when triggered reverses inhibitory effects on growth and promotes axon regeneration,” commented Shuxin Li, MD, PhD, professor of anatomy and cell biology at Shriners Hospital’s Pediatric Research Center at LKSOM, and a senior investigator on the new study, which is titled, “Glial Metabolic Rewiring Promotes Axon Regeneration and Functional Recovery in the Central Nervous System.”
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RhoA Protein Function Identified in Nerve Cell Development
Posted on November 4th, 2019
A recent study has revealed new findings about nerve cell development that could help to facilitate future treatment options for spinal cord injuries.
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Nerve Cells Regrown In Rats With Spinal Cord Injury
Posted on July 1st, 2013
Researchers at the Case Western Medical School and the Cleveland Clinic have developed a technique that regenerates nerve cells in rats, permitting them to urinate normally after severe spinal cord injury. The results of their research are published in today’s edition of the Journal of Neuroscience.
According to scientists Yu-Shang Lee and Jerry Silver, their technique raises hope that humans with such injuries may also be able to restore bladder and other functions.
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Stem Cell Treatment Repairs Spinal Cord Injuries In Paralyzed Dogs
Posted on November 25th, 2012
Scientists have used a special cell to regenerate damaged parts of dogs’ spines. Researchers are cautiously excited about these results which could potentially have a future role in the treatment of human patients with similar spinal injuries.
For many years, scientists have been aware that olfactory ensheathing cells (OEC) could be helpful in treating the damaged spinal cord because of their distinctive properties. The unique cells have the capacity to support nerve fiber growth that preserves a pathway between the nose and the brain.
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