Category: ‘Research for a Cure’
Posted on July 20th, 2020
Most people with spinal cord injury are paralyzed from the injury site down, even when the cord isn’t completely severed. Why don’t the spared portions of the spinal cord keep working? Researchers at Boston Children’s Hospital now provide insight into why these nerve pathways remain quiet. They also show that a small-molecule compound, given systemically, can revive these circuits in paralyzed mice, restoring their ability to walk.
Posted on June 8th, 2020
Precise control over neuron growth paves the way for repairing injuries, improving brain models.
Harvard University researchers have developed an engineering technique to precisely control the direction that neurons grow their axons, cable-like structures that allow nerve cells to connect with each other. In a zebrafish model, researchers used the approach to correct defective neural connections and restore the neuron’s ability to cause muscle contractions.
Posted on May 16th, 2020
Scientists have discovered a new treatment to dramatically reduce swelling after brain and spinal cord injuries, offering hope to 75 million victims worldwide each year.
The breakthrough in treating such injuries – referred to as central nervous system (CNS) oedema – is thought to be hugely significant because current options are limited to putting patients in an induced coma or performing risky surgery.
Posted on April 30th, 2020
Like power lines in an electrical grid, long wiry projections that grow outward from neurons – structures known as axons – form interconnected communication networks that run from the brain to all parts of the body. But unlike an outage in a power line, which can be fixed, a break in an axon is permanent. Each year thousands of patients confront this reality, facing life-long losses in sensation and motor function from spinal cord injury and related conditions in which axons are badly damaged or severed.
Posted on April 24th, 2020
The lack of sensation that accompanies paralysis is an additional burden that has, until now, been a problem that science has not been able to remedy.