Category: ‘Research for a Cure’


Putting a Protein into Overdrive to Heal Spinal Cord Injuries

Posted on March 6th, 2021

Scar-forming cells that overproduce the protein SOX2 made new neurons, improving recovery in mice

New Spinal Neurons

Using genetic engineering, researchers at UT Southwestern and Indiana University have reprogrammed scar-forming cells in mouse spinal cords to create new nerve cells, spurring recovery after spinal cord injury. The findings, published online today in Cell Stem Cell, could offer hope for the hundreds of thousands of people worldwide who suffer a spinal cord injury each year.

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Yale Scientists Repair Injured Spinal Cord Using Patients’ Own Stem Cells

Posted on February 22nd, 2021

Stem Cells, Cellular Therapy

Intravenous injection of bone marrow derived stem cells (MSCs) in patients with spinal cord injuries led to significant improvement in motor functions, researchers from Yale University and Japan report Feb. 18 in the Journal of Clinical Neurology and Neurosurgery.

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Designer Cytokine Makes Paralyzed Mice Walk Again

Posted on January 16th, 2021

Using gene therapy, a research team has succeeded for the first time in getting mice to walk again after a complete cross-sectional injury. The nerve cells produced the curative protein themselves.

Paralyzed Mice Began to Walk
Two to three weeks after treatment, the previously paralyzed mice began to walk. © Lehrstuhl für Zellphysiologie

To date, paralysis resulting from spinal cord damage has been irreparable. With a new therapeutic approach, scientists from the Department for Cell Physiology at Ruhr-Universität Bochum (RUB) headed by Professor Dietmar Fischer have succeeded for the first time in getting paralyzed mice to walk again. The keys to this are the protein hyper-interleukin-6, which stimulates nerve cells to regenerate, and the way how it is supplied to the animals. The researchers published their report in the Journal Nature Communications from15 January 2021.

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New Treatment Allows Some People with Spinal Cord Injury to Regain Hand and Arm Function

Posted on January 12th, 2021

Almost 18,000 Americans experience traumatic spinal cord injuries every year. Many of these people are unable to use their hands and arms and can’t do everyday tasks such as eating, grooming or drinking water without help.

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Scientists Successfully Regrow Optic Nerve Cells

Posted on November 6th, 2020

Scientists have successfully regenerated damaged optic nerve cells from mice by stimulating production of a certain protein, providing hope for breakthrough treatments of numerous human eye diseases.

A close-up of a human eye.

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