Category: ‘Research for a Cure’


Scientists Find a New Way to Regrow Nerves in Spinal Injuries

Posted on March 13th, 2020

In experiments on rats with spinal cord injuries, the rodents improved their walking ability following treatment.

Neuronal growth before and after.
Neuronal growth before, left, and after, right, the team’s treatment

New research from the University of Aberdeen has found a new way to repair injured spinal nerves.

Researchers achieved significant regrowth of injured spinal nerves in rats when they activated a specific molecule found in nerve cells.

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Scientists Study Link Between Energy Levels, Spinal Cord Injury

Posted on March 4th, 2020

Energy Levels and Axon Growth

Each year, thousands of people in the United States experience a spinal cord injury, damaging the system of nerves that the brain and body use to communicate.

A team of researchers from Indiana University School of Medicine, in collaboration with the National Institute of Neurological Disorders and Stroke, have investigated how boosting energy levels within damaged nerve fibers or axons may represent a novel therapeutic direction for axonal regeneration and functional recovery.

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Researchers Identify a Protein That Is Critical for Wound Healing after Spinal Cod Injury

Posted on March 3rd, 2020

Plexin-B2, an axon guidance protein in the central nervous system (CNS), plays an important role in wound healing and neural repair following spinal cord injury (SCI), according to research conducted at the Icahn School of Medicine at Mount Sinai and published today in Nature Neuroscience. The study’s findings could aid the development of therapies that target axon guidance pathways for more effective treatment of SCI patients. 

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Growth Factor-Modified Stem Cells Help Repair Spinal Cord Injuries in Rats

Posted on February 20th, 2020

Stem Cell Research

A new study released today in STEM CELLS Translational Medicine is the first to illustrate the presence of oxygen-deprived clusters throughout the damaged site of a compressed spinal cord. It is also the first to show how transplanting basic growth factor with the use of a viral vector to target the oxygen-deprived sites enhances the injured spinal cord’s recovery.

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New Injection Technique May Boost Spinal Cord Injury Repair

Posted on January 31st, 2020

Efforts In rodent studies, method reduced likelihood of further spinal cord trauma while delivering large doses of potentially reparative stem cells; the approach may have utility for multiple neurodegenerative conditions.

Injection Site
A micrograph shows effective migration of subpially injected human oligodendrocytes (a type of support cell in the central nervous system, colored here in green) into the spinal cord gray matter (left) and into the cerebellum (right) of an immunodeficient rat. Red indicates signal for oligodendrocyte marker; blue is signal for neuronal marker.

Writing in the journal Stem Cells Translational Medicine, an international research team, led by physician-scientists at University of California San Diego School of Medicine, describe a new method for delivering neural precursor cells (NSCs) to spinal cord injuries in rats, reducing the risk of further injury and boosting the propagation of potentially reparative cells.

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