Category: ‘Research for a Cure’


Smart Drug Delivery System May Help Treat Spinal Cord Injuries, Neurological Disorders

Posted on September 19th, 2020

Drug delivery technology is aimed at helping people with spinal cord and other nervous system disorders.

Drug delivery system.
This drug delivery system includes a porous biodegradable platform that can reduce nervous tissue inflammation and may help treat spinal cord injuries and other neurological disorders. Image: KiBum Lee, Letao Yang and Brian M. Conley

A Rutgers-led team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and other neurological disorders.

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Glial Cell Metabolism Linked with Functional Regeneration of CNS Neurons

Posted on September 19th, 2020

High quality 3d render of nerve cells, concept for Neurologic Diseases, tumors and brain surgery.

Scientists at the Lewis Katz School of Medicine at Temple University (LKSOM) and the University of Pennsylvania have demonstrated how astrocytic glial cells in the brain can play a major role in facilitating neuron repair. The research, reported in Cell Metabolism, is the first to establish a link between glucose metabolism in glial cells and functional regeneration of damaged neurons in the central nervous system. “We found that glia have a metabolic switch associated with glucose metabolism that when triggered reverses inhibitory effects on growth and promotes axon regeneration,” commented Shuxin Li, MD, PhD, professor of anatomy and cell biology at Shriners Hospital’s Pediatric Research Center at LKSOM, and a senior investigator on the new study, which is titled, “Glial Metabolic Rewiring Promotes Axon Regeneration and Functional Recovery in the Central Nervous System.”

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Neuralink Reveals Working Brain-to-Machine Interface

Posted on September 2nd, 2020

In a live demonstration, Elon Musk revealed that Neuralink has successfully installed a working brain-to-machine interface inside a pig.

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Re-Engineered Enzyme Could Help Reverse Damage from Stroke, Spinal Cord Injury

Posted on August 26th, 2020

A rendering of the enzyme chondroitinase ABC
A rendering of the enzyme chondroitinase ABC (Hettiaratchi, O’Meara et al., 2020. DOI: 10.1126/sciadv.abc6378 This work is licensed under CC BY-NC)

A team of researchers from the University of Toronto’s Faculty of Applied Science & Engineering and the University of Michigan has redesigned and enhanced a natural enzyme that shows promise in promoting the regrowth of nerve tissue following injury.

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Improving Treatment of Spinal Cord Injuries

Posted on August 14th, 2020

Osmotic therapy device reduces swelling to prevent secondary injuries in rats

When injured, the spinal cord swells, restricting blood flow and causing critical and permanent motor, sensory, and autonomic function damage. Rapid prevention of spinal cord swelling immediately after injury is key to preventing more serious damage. The only treatment to date has been steroid therapy with methylprednisolone, which is minimally effective.

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