Category: ‘Clinical Trials and Studies’


Scientists Make Breakthrough in Spinal Cord Stem Cell Treatment

Posted on March 24th, 2025

A Medical Imaging Examination of the Spine

A stem cell treatment helped improve the motor function of two out of four patients with a spinal cord injury in the first clinical study of its kind, Japanese scientists said.

There is currently no effective treatment for paralysis caused by serious spinal cord injuries, which affect more than 150,000 patients in Japan alone, with 5,000 new cases each year.

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Neural Stem Cell Transplantation Shows Promise for Treating Chronic Spinal Cord Injury

Posted on December 17th, 2024

Neural Stem Cells
Neural stem cells, shown here, can be made to develop into the varied types of cells found in the nervous system. Photo credit: Welcome Collection/Wikimedia Commons

A Phase I clinical trial led by researchers at University of California San Diego School of Medicine has demonstrated the long-term safety and feasibility of neural stem cell transplantation for treating chronic spinal cord injuries. These devastating injuries often result in partial or full paralysis and are currently incurable. The study, which followed four patients with chronic spinal cord injuries for five years, found that two patients showed durable evidence of neurological improvement after treatment with neural stem cell implantation, including increased motor and sensory scores, and improved electromyography (EMG) activity. Some patients also showed improvement in pain scores.

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World-First Clinical Trial for Treating Spinal Cord Injury

Posted on October 21st, 2024

Since the passing of Professor Emeritus Alan Mackay-Sim AM in 2023, his ground-breaking legacy research is about to be realized with a Phase I human clinical trial commencing to test the efficacy and safety of the transplantation of olfactory cell nerve bridges to treat chronic spinal cord injury.

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Device Restores Hand Function for Some with Spinal Injury

Posted on May 20th, 2024

In a study, people with paralysis saw arm strength and function improve via electrical stimulation to the injured area.

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Elon Musk’s Neuralink to Start Human Trial of Brain Implant

Posted on September 20th, 2023

Billionaire entrepreneur Elon Musk’s brain-chip startup Neuralink said on Tuesday it has received approval from an independent review board to begin recruitment for the first human trial of its brain implant for paralysis patients.

Those with paralysis due to cervical spinal cord injury or amyotrophic lateral sclerosis may qualify for the study, it said, but did not reveal how many participants would be enrolled in the trial, which will take about six years to complete.

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